朱钢国 博士 教授省“万人计划”科技创新领军人才

E-mail: gangguo@zjnu.cn

基本情况如下：

1996年9月－2000年7月：浙江师范大学化学系，理学学士。2000年9月－2005年7月：中科院上海有机化学研究所，理学博士，导师张兆国教授。2005年9月－2007年10月：美国普渡大学博士后，导师诺贝尔化学奖得主Negishi教授。2007年11月－2008年10月：美国印第安纳大学博士后。2008年12月－今：浙江师范大学化学系，先后为校聘教授、教授（2011.12）、博导，历任化学与生命科学学院副院长、院长、化学与材料科学学院院长。2024年7月－今：任金华职业技术大学副校长。2013年入选浙江省高校中青年学科带头人，2016年入选浙江省“151”人才工程第二层次培养对象、浙江师范大学首批“双龙学者”特聘教授，2020年入选省“万人计划”科技创新领军人才、省高校中青年领军人才，获2016-2018年省“三育人”先进个人，现为中国化学会高级会员、省化学会常务理事、金华市人大常委，以通讯作者发表Angew. Chem. Int. Ed.（3篇）、Nat. Commun. （2篇）、Chem. Sci. （2篇）等SCI论文90多篇，授权发明专利10多件，先后主持国家自然科学基金5项、浙江省自然科学基金杰出青年项目、重点项目等省部级项目5项，完成横向项目4项，曾指导学生获“挑战杯”竞赛全国二等奖、浙江省一等奖、负责省级精品在线开放课程1门，主要从事自由基化学、有机氟化学和药物中间体合成研究。

获奖：

1、2019 Thieme Chemistry Journal Award。

2、2015年浙江省自然科学奖三等奖：杂原子取代炔烃的亲核金属化反应方法学研究（第一完成人）；

3、2012年度浙江省高校优秀科研成果奖一等奖：杂原子取代炔烃的亲核钯化反应方法学研究（第一完成人）。

    主持项目：

1、 国家自然科学基金面上项目：氟效应促进的氟烷基取代烯烃α-烷基化反应研究(22371262)；

2、 国家自然科学基金面上项目：自由基加成启动的非末端炔烃远程碳-氢键官能团化反应研究(22071218)；

3、 国家自然科学基金面上项目：过渡金属催化的醛直接转化为酮的自由基反应研究(21672191) ，已结题；

4、 国家自然科学基金面上项目：基于1,2-双官能团化烯烃的偶联反应选择性合成多取代烯烃(21172199)，已结题；

5、 国家自然科学基金青年基金：偶极烯丙基钯的环加成反应研究(20902084)，已结题；

6、 浙江省自然科学基金杰出青年项目：1-卤-1-硫代烯烃的立体选择性合成及其三取代烯烃的构建(LR12B02001)，已结题；

7、 浙江省自然科学基金重点项目：杂原子取代炔烃自由基加成启动的远程sp3碳-氢键官能团化反应研究(LZ20B020001) ，已结题；

8、 浙江省公益性技术应用研究计划项目：2-氨基呋喃化学品的催化合成技术研究(2015C31030) ，已结题；

9、 浙江省钱江人才计划项目：抗禽流感药物达菲的合成工艺研究(2010R10016)，已结题。

论文发表：

2024年

1. Tetrafluoroisopropylation of alkenes and alkynes enabled by photocatalytic consecutive difluoromethylation with CF₂HSO₂Na, Hong, Y.; Qiu, J.; Wu, Z.; Xu, S.; Zheng, H.*; Zhu, G.* Nat. Commun. 2024, 15, 5685.

2. A Fluorine-Effect-Enabled Photocatalytic 4-Exo-Trig Cyclization Cascade to Access Fluoroalkylated Cyclobutanes, Zhou, Y.; Wu, Z.; Xu, J.; Zhang, Z.; Zheng, H.*; Zhu, G.* Angew. Chem. Int. Ed. 2024, 63, e202405678 (研究成果被浙江省自然科学基金委等网站报道：https://zjnsf.kjt.zj.gov.cn/api/site/v1/post/detail?categoryId=2018629&postId=1242760770937159680).

3. Recent advances of 5-endo-trig radical cyclization: promoting strategies and applications, Zhou, Y.; Xu, S.; Zhang, X.; Zhou, L.; Zheng, H.*; Zhu, G.* Chem. Commun. 2024, 60, 10098-10111.

4. Controllable Synthesis of Cyclopenta[b]indolines via Photocatalytic Fluoroalkylative Radical Cyclization Cascade of Ynamides, Li, J.; Zhou, Y.; Luo, J.; Chen, H.; Qi, H.; Zheng, H.*; Zhu, G.* Org. Lett. 2024, 26, 4643-4647.

5. Photocatalytic [3+2] Cycloaddition of Alkyl/aryl Iodides and Internal Alkynes by Merging Halogen and Hydrogen Atom Transfer, Gu, Z.; Jia, R.; Zeng, T.; Zheng, H.*; Zhu, G.* Chin. J. Chem. 2024, 42, 2329-2334.

6. Controllable Synthesis of Fully-Substituted Alkyl Vinyl Ethers Enabled by Dual-Functional Copper Catalysis, Zheng, H.; Zhu, G.* Chin. J. Org. Chem. 2024, 44, 1043-1044.

7. Visible-Light-Driven Formyl Group Migration Triggered Remote Desaturation, Hong, Y.; Qin, Y.; Yang, X.; Zhou, L.; Yuan, Y.*; Zhu, G.* Eur. J. Org. Chem. 2024, e202400405.

8. Direct C(sp²)–H activation of allenes via hydrogenatom transfer (HAT) in organic synthesis, Chen, J.-Q.; Zhu, G.*; Wu, J. Org. Chem. Front. 2024, 11, 2108-2111.

9. Recent Advances on Hydrogen Atom Transfer Induced C(sp³)-H Functionalizations Initiated by Radical Addition to Alkynes, Zhou, Y.; Gu, Z.; Hong, Y.; Chen, H.; Luo, J.; Zheng, H.*; Zhu, G.* Org. Chem. Front. 2024, 11, 1232-1250.

2023年

10. Diastereoselective Construction of α-Fluoroalkyl Cycloalkanols via Radical Alkylation of α-Fluoroalkyl Ketones, Liu, Y.; Li, J.; Zhou, Y.; Zheng, H.*; Shen, Z.; Zhu, G.* Chin. J. Chem. 2023, 41, 3275-3280.

11. Construction of Difluoroalkylated Cyclopentenones through Photocatalytic Difluoroalkylative 5-Endo Cyclization Cascades of Ynones, Su, J.; Xu, J.; Gu, Z.; Zhou, Y.; Zheng, H.*; Zhu, G.* Eur. J. Org. Chem. 2023, e202300432.

12. Cu-catalyzed cascade difluoroalkylation/5-endo cyclization/β-fluorine cleavage of ynones, Su, J.; Guo, W.; Liu, Y.; Kong, L.; Zheng, H.*; Zhu, G.* Chem. Commun. 2023, 59, 1821-1824.

2022年

13. Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes, Zhou, Y.; Qin, Y.; Wang, Q.; Zhang, Z.; Zhu, G.* Angew. Chem. Int. Ed. 2022, 61, e202110864. Highlighted by https://www.x-mol.com/news/733556. https://www.organic-chemistry.org/Highlights/2022/31October.shtm. Top Downloaded Article during its first 12 months of publication.

14. [3+2] Cycloaddition of alkyl aldehydes and alkynes enabled by photoinduced hydrogen atom transfer, Le, S.; Li, J.; Feng, J.; Zhang, Z.; Bai, Y.; Yuan Z.; Zhu, G.* Nat. Commun. 2022, 13, 4734.

15. Recent Advances on 5-Endo-Trig Radical Cyclization of All-Carbon Systems, Zheng, H.; Su, J.; Zhou, Y.; Zhu, G.* Chin. J. Org. Chem. 2022, 42, 4060-4066.

16. A diastereoselective synthesis of cyclopentanones via photocatalytic reductive alkyltrifluoromethylation of ynones, Qiu, J.;^† Le, S.;^† Su, J.; Liu, Y.; Zhou, Y.; Zheng, H.; Bai, Y.; Zhu, G.* Org. Chem. Front. 2022, 9, 5523-5529.

17. Access to cyclopentenones via copper-catalyzed 5-endo trifluoromethylcarbocyclization of ynones, Le, S.;^‡ Bai, Y.;^‡ Qiu, J.; Zhang, Z.; Zheng, H.* Zhu, G.* Org. Chem. Front. 2022, 9, 4670-4675.

18. Copper-Catalyzed 1,2,5-Trifunctionalization of Terminal Alkynes Using SR as a Transient Directing Group for Radical Translocation, Feng, J.;^‡ Zhang, F.;^‡ Shu, C.; Zhu, G.* Chin. J. Chem. 2022, 40, 1667-1673.

2021年

19. Radical Chain Isomerization of N-Sulfonyl Ynamides to Ketenimines and Its Application to Furan Dearomatization, Shen, J.;^‡ Wu, Z.;^‡ Liu, Y.; Bai, Y.; Qiu, J.; Zhang, Z.; Yuan, Z.;* Zhu, G.* Org. Lett. 2021, 23, 9321-9326.

20. Solvent-controlled photocatalytic divergent cyclization of alkynyl aldehydes: access to cyclopentenones and dihydropyranols, Zhu, H.;^‡ Zheng, H.;^‡ Zhang, J.;^‡ Feng, J.; Kong, L.; Zhang, F.; Xue, X.-S.;* Zhu, G.* Chem. Sci. 2021, 12, 11420-11426.

21. Synthesis of polysubstituted azetidines via cascade trifluoromethylation/cyclization of N-allyl ynamides, Zhou, G.; Su, J.; Shang, T.; Wang, X.; Bai, Y.*; Yuan, Z.*; Zhu, G.* Org. Chem. Front. 2021, 8, 4473-4478.

22. Transition-Metal-Free α Csp³−H Cyanation of Sulfonamides, Zhou, L.; Wei, S.; Lei, Z.; Zhu, G.*; Zhang, Z.* Chem. Eur. J. 2021, 27, 7103-7107.

2020年

23. Internal Alkyne-Directed Fluorination of Unactivated C(sp³)-H Bonds, Shu, C.; Feng, J.; Zheng, H.; Cheng, C.; Yuan, Z.; Zhang, Z.; Xue, X.-S.; Zhu, G.* Org. Lett. 2020, 22, 9398-9403. Highlighted by Synfacts 2021, 17, 182.

24. Synthesis of Polysubstituted Pyrroles via Silver-Catalyzed Oxidative Radical Addition of Cyclopropanols to Imines, Zhou, Y.; Wu, M.; Liu, Y.; Cheng, C.; Zhu, G.* Org. Lett. 2020, 22, 7542-7546.

25. Visible-Light Photocatalytic Remote Halo-Difluoroalkylation of Thioalkynes, Zhu, H.; Shang, T.;  Lu, Z.; Luo, F.; Zhu, G.* Chin. J. Org. Chem. 2020, 40, 3410-3419 (invited paper, 庆祝黄乃正先生七十华诞专辑).

26. AIBN-Induced Remote Trifluoromethyl-Alkynylation of Thioalkynes, Xiong, Z.; Zhang, F.; Yu, Y.; Tan, Z.; Zhu, G.* Org. Lett. 2020, 22, 4088-4092.

27. Photocatalytic Remote Oxyfluoroalkylation of Heteroalkynes: Regio-, Stereo-, and Site-Selective Access to Complex Fluoroalkylated (Z)-Alkenes, Shang, T.; Zhang, J.; Zhang, Y.; Zhang, F.; Li, X.-S.*; Zhu, G.* Org. Lett. 2020, 22, 3667-3672. 

2019年

28. Visible-Light Photocatalytic Remote Thiolation of Aldehydes Triggered by Sulfonylation of Alkenes With Thiosulfonates, Yang, J.; Fu, X.; Lu, Z.; Zhu, G.* Acta Chim. Sinica 2019, 77, 901-905 (invited paper).

29. Photocatalytic 1,1-Hydrofluoroalkylation of Alkynes with A Concurrent Vicinal Acylation: An Access to Fluoroalkylated Cyclic Ketones, Wan, Y.; Shang, T.; Lu, Z. Zhu, G.* Org. Lett. 2019, 21, 4187-4191.

30. Visible light photocatalytic acyldifluoroalkylation of unactivated alkenes for the direct synthesis of gem-difluorinated ketones, Zhou, Y.; Xiong, Z.; Qiu, J.; Kong, L.*; Zhu, G.* Org. Chem. Front. 2019, 6, 1022-1026. 

31. Modular Synthesis of Alkylarylazo Compounds via Iron(III)-Catalyzed Olefin Hydroamination, Zhang, Y.*; Huang, C.; Lin, X.; Hu, Q.; Hu, B.; Zhou, Y.; Zhu, G.* Org. Lett. 2019, 21, 2261-2264.

32. Multicomponent Synthesis of Isoindolinones by Rh^III Relay Catalysis: Synthesis of Pagoclone and Pazinaclone from Benzaldehyde, Zhang, Y.*; Zhu, H.; Huang, Y.; Hu, Q.; He, Y.; Wen, Y.; Zhu, G.* Org. Lett. 2019, 21, 1273-1277.

2018年

33. Recent Advances on Oxidative Radical Addition to Aldehydes, Kong, L.; Zhou, Y.; Luo, F.; Zhu, G.* Chin. J. Org. Chem. 2018, 38, 2858-2865 (invited paper).

34. Palladium-Catalyzed anti-Selective Fluoroalkylboration of Internal and Terminal Alkynes, Wang, S.; Zhang, J.; Kong, L.; Tan, Z.; Bai, Y.^*; Zhu, G.* Org. Lett. 2018, 20, 5631-5635.

35. Visible-light induced three-component alkynyl-difluoroalkylation of unactivated alkenes, Jin, W.; Wu, M.; Xiong, Z. Zhu, G.* Chem. Commun. 2018, 54, 7924-7927.  

36. Synthesis of Difluoromethylated and Phosphorated Spiro[5.5]trienones via Dearomative Spirocyclization of Biaryl Ynones, Zhang, Y.*; Zhang, J.; Hu, B.; Ji, M.; Ye, S.; Zhu, G.* Org. Lett. 2018, 20, 2988-2992. 

37. Photocatalytic acylarylation of unactivated alkenes with diaryliodonium salts toward indanones and related compounds, Chen, Y.; Shu, C.; Luo, F.; Xiao, X.;^* Zhu, G.* Chem. Commun. 2018, 54, 5373-5376.

38. Intermolecular Oxidative Radical Addition to Aromatic Aldehydes: Direct Access to 1,4- and 1,5-Diketones via Silver-Catalyzed Ring-Opening Acylation of Cyclopropanols and Cyclobutanols, Che, C.; Qian, Z.; Wu, M.; Zhao, Y.; Zhu, G.* J. Org. Chem. 2018, 83, 5665-5673.

39. Nickel-Catalyzed Remote Arylation of Alkenyl Aldehydes Initiated by Radical Alkylation with Tertiary α-Carbonyl Alkyl Bromides, Jin, W.; Zhou, Y.; Zhao, Y.; Ma, Q.; Kong, L.; Zhu, G.* Org. Lett. 2018, 20, 1435-1438.

40. Palladium-Catalyzed Site-Selective sp³ C-H Bond Thiocyanation of 2-Aminofurans, Chen, Y.; Wang, S.; Jiang, Q.; Cheng, C.; Xiao, X.;* Zhu, G.* J. Org. Chem. 2018, 83, 716-722.

2017年

41. Palladium-Catalyzed Remote Aryldifluoroalkylation of Alkenyl Aldehydes, Nie, X.; Cheng, C.; Zhu, G.* Angew. Chem. Int. Ed. 2017, 56, 1898-1902.

42. Preparation of 2-Amino-5-homoallylfurans via Palladium-Catalyzed Tandem Cycloisomerization/Heck-Type Coupling of Homoallenyl Amides with Allyltrialkylsilanes, Zhang, J.; Wu, M.; Lu, W.; Wang, S.; Zhang, Y.; Cheng, C.;* Zhu, G.* J. Org. Chem. 2017, 82, 11134-11140.

43. Palladium-catalyzed tandem cyclization/sulfonylation of homoallenyl amides with sodium sulfinates, Wan, Y.; Zhang, J.; Chen, Y.; Kong, L.; Luo, F.;* Zhu, G.* Org. Biomol. Chem. 2017, 15, 7204-7211.

44. Copper-Catalyzed Radical Cascade Difluoromethylation/Cyclization of 2-(3-Arylpropioloyl)benzaldehydes: A Route to Difluoromethylated Naphthoquinones, Zhang, Y.*; Ye, S.(本科生); Ji, M.; Li, L.; Guo, D.; Zhu, G. J. Org. Chem. 2017, 82, 6811-6818.

45. Visible Light-Induced Tandem Radical Addition-Cyclization of Alkenyl Aldehydes Leading to Indanones and Related Compounds, Lu, D.; Wan, Y.; Kong, L.; Zhu, G.* Org. Lett. 2017, 19, 2929-2932.

46. Copper-catalyzed acyltrifluoromethylation of alkenes: rapid access to trifluoroethyl indanones and related compounds, Liu, Z.; Bai, Y.; Zhang, J.; Yu, Y.; Tan, Z.; Zhu, G.* Chem. Commun. 2017, 53, 6440-6443.  

47. 

48. Synthesis of Trifluoromethylated Naphthoquinones via Copper-Catalyzed Cascade Trifluoromethylation/Cyclization of 2-(3-Arylpropioloyl)benzaldehydes, Zhang, Y.;^* Guo, D.(本科生); Ye, S.; Liu, Z.; Zhu, G.* Org. Lett. 2017, 19, 1302-1305.

49. Copper-catalyzed borylative cyclization of 1,n-enynyl phosphates leading to five- to eight-membered cyclic 1,4-dienyl boronates, Zhang, F.; Wang, S.; Liu, Z.; Bai, Y.;* Zhu, G.* Tetrahedron Lett. 2017, 58, 1448-1452.

2016年

50. Synthesis of (E)-α,β-Unsaturated Carbonyls via Silver-Catalyzed Tandem Epoxide Rearrangement/Intermolecular Carbonyl-Heteroalkyne Metathesis, Zhu, H.; Jin, W.; He, J.; Zhang, Y.*; Zhu, G.* Adv. Synth. Catal. 2016, 358, 3730-3735.

51. Copper-catalyzed cascade annulation between α-bromocarbonyls and biaryl or (Z)-arylvinylacetylenes enabling a direct synthesis of dibenzocycloheptanes and related compounds, Lu, D.; Wan, Y.; Kong, L.; Zhu, G.* Chem. Commun. 2016, 52, 13971-13974.

52. Copper-Catalyzed Trifluoromethylation of Alkenes with Redox-Neutral Remote Amidation of Aldehydes, Cheng, C.; Liu, S.; Lu, D.; Zhu, G.* Org. Lett. 2016, 18, 2852-2855.

53. Copper-catalyzed cascade annulation of unsaturated α-bromocarbonyls with enynals: a facile access to ketones from aldehydes, Che, C.; Huang, Q.; Zheng, H.; Zhu, G.* Chem. Sci. 2016, 7, 4134-4139. 

54. Direct access to 2-amino-5-azidomethylfurans through palladium-catalyzed azidative cycloisomerization of homoallenyl amides, Huang, Q.(本科生); Zheng, H.; Liu, S.; Kong, L.; Luo, F.*; Zhu, G.* Org. Biomol. Chem. 2016, 14, 8557-8563.

55. HOTf-Catalyzed, Solvent-free Oxyarylation of Ynol Ethers and Thioethers, Hu, L.; Cui, Q.; Chen, X.; Tan, Z.*; Zhu, G.* J. Org. Chem. 2016, 81, 4861-4868.

56. Copper-catalyzed coupling of 2-vinyl benzaldehydes with 3-alkenyl 2-bromocarbonyls for the rapid construction of 3,4-cyclopenta-1-tetralones, Zhu, H.; Nie, X.; Huang, Q.; Zhu G.* Tetrahedron Lett. 2016, 57, 2331-2335.

57. Highly mono-selective ortho-trifluoromethylation of benzamides via 8-aminoquinoline assisted Cu-promoted C-H activations, Hu, L.; Chen, X.; Gui, Q.; Tan, Z.*, Zhu, G. Chem. Commun. 2016, 52, 6845-6848. 

2015年

58. A rapid and selective synthesis of α,α-fluorohalo esters via fluorohalogenative or difluorinative hydration of ynol ethers, Hu, L.; Che, C.; Tan, Z.;* Zhu, G.* Chem. Commun. 2015, 51, 16641-16644.

59. Construction of 1-Naphthols via Benzannulation Based on the Reaction of Aryl tert-Butyl Ynol Ethers with Ynamides or Ynol Ethers, Bai, Y.; Yin, J.; Liu, Z.; Zhu, G.* J. Org. Chem. 2015, 80, 10226-10233.

60. Copper-Catalyzed trans-Carbohalogenation of Terminal Alkynes with Functionalized Tertiary Alkyl Halides, Che, C.; Zheng, H.; Zhu, G.* Org. Lett. 2015, 17, 1617-1620.

61. Palladium-Catalyzed Cycloisomerization and Aerobic Oxidative Cycloisomerization of Homoallenyl Amides: A Facile and Divergent Approach to 2-Aminofurans, Cheng, C.; Liu, S.; Zhu, G.* Org. Lett. 2015, 17, 1581-1584. 

62. Copper-catalyzed regio- and stereoselective hydroallylation of thioalkynes with allylboronates: a facile and convenient synthesis of 1,4-dienes, Kong, W.; Che, C.; Kong, L.*; Zhu, G.* Tetrahedron Lett. 2015, 56, 2780-2782.

63. Copper-Catalyzed β-Selective Borylation of Ynamides: A Facile Access to (E)-β-Alkenylamide Boronates, Bai, Y.*; Zhang, F.; Shen, J.; Luo, F.; Zhu, G.* Asian J. Org. Chem. 2015, 4, 626-629 (Dedicated to Prof. Ei-ichi Negishi on the occasion of his 80th birthday)

64. Divergent Synthesis of 2-Aminofurans via Palladium-Catalyzed Acetoxylative, Alkoxylative, and Hydroxylative Cycloisomerization of Homoallenyl Amides, Cheng, C.; Liu, S.; Zhu, G.* J. Org. Chem. 2015, 80, 7604-7612.

2014年

65. Palladium-Catalyzed Cross Addition of Terminal Alkynes to Aryl Ynamides: An Unusual trans-Hydroalkynylation Reaction, Liu, G.; Kong, W.; Che, J.; Zhu, G.* Adv. Synth. Catal. 2014, 356, 3314-3318.

66. Preparation of (Z)-α,β-Disubstituted Enamides via Palladium-Catalyzed Addition of Boronic Acids to Ynamides, Yang, Y.; Wang, L.; Zhang, F.; Zhu. G.* J. Org. Chem. 2014, 79, 9319-9324.  

67. Silver-Catalyzed Regio- and Stereoselective Addition of Carboxylic Acids to Ynol Ethers, Yin, J.; Bai, Y.; Mao, M.; Zhu. G.* J. Org. Chem. 2014, 79, 9179-9185.  

68. Silver-promoted trans-hydrofluorination of ynamides: a regio- and stereoselective approach to (Z)-α-fluoroenamides, Che, J.(本科生); Li, Y.; Zhang, F.; Zheng, R.*; Bai, Y.; Zhu. G.* Tetrahedron Lett. 2014, 55, 6240-6242.  

69. Pd-Catalyzed Regio- and Stereoselective Addition of Boronic Acids to Silylacetylenes: A Stereodivergent Assembly of β,β-Disubstituted Alkenyl Silanes and Alkenyl Halides, Kong, W.; Che, C.; Wu, J.; Ma, L.; Zhu, G.* J. Org. Chem. 2014, 79, 5799-5805.  

70. Palladium-Catalyzed Hydroarylation, Hydroalkenylation, and Hydrobenzylation of Ynol Ethers with Organohalides: A Regio- and Stereoselective Entry to α,β- and β,β-Disubstituted Alkenyl Ethers, Cui, W.; Ying, J.; Zheng, R.; Cheng, C.; Bai, Y. Zhu, G.* J. Org. Chem. 2014, 79, 3487-3493.  

71. An unprecedented Pd-catalyzed trans-addition of boronic acids to ynamides. Yang, Y.; Wang, L.; Zhang, J.; Jin, Y.; Zhu, G.* Chem. Commun. 2014, 50, 2347-2349.

72. Synthesis of cis-1,2-dichlorovinylsulfones via Fe-catalyzed regio- and stereoselective addition of sulfonyl chlorides to aromatic chloroalkynes. Wang, L.; Zhu, H.; Che, J.; Yang, Y.*; Zhu, G.* Tetrahedron Lett. 2014, 55, 1011-1013.  

73. Synthesis of (Z)-1-Thio- and (Z)-2-Thio-1-alkenyl Boronates via Copper-Catalyzed Regiodivergent Hydroboration of Thioacetylenes: An Experimental and Theoretical Study. Zhu, G.*; Kong, W.; Feng, H.; Qian, Z.* J. Org. Chem. 2014, 79, 1786-1795.

74. A regio- and stereoselective entry to (Z)-β-halo alkenyl sulfides and their applications to the access of stereodefined trisubstituted alkenes. Liu, G.; Kong, L.; Shen, J.; Zhu, G.* Org. Biomol. Chem. 2014, 12, 2310-2321. 

2013年

75. Palladium-Catalyzed Direct Alkenylation of 2-Oxazolones: An Entry to 3,4,5-Trisubstituted 2-Oxazolones, Lu, Z.; Luo, F.; Wang, L.; Zhu, G.* J. Org. Chem. 2013, 78, 10894-10901.

76. Pd-catalyzed addition of boronic acids to ynol ethers: a highly regio- and stereoselective synthesis of trisubstituted vinyl ethers. Bai, Y.; Yin, J.; Kong, W.; Mao, M.; Zhu, G.* Chem. Commun. 2013, 49, 7650-7652.

77. Regioselective and Stereoselective Entry to β,β-Disubstituted Vinyl Ethers via the Sequential Hydroboration/Suzuki–Miyaura Coupling of Ynol Ethers. Cui, W.; Mao, M.; He, Z.; Zhu, G.* J. Org. Chem. 2013, 78, 9815-9821.

78. Copper-catalyzed direct thiolation of xanthines and related heterocycles with disulfides. He, Z. (本科生); Luo, F.;* Li, Y.; Zhu, G.* Tetrahedron Lett. 2013, 54, 5907-5910.

79. An operationally simple approach to (E)-α-halo vinyl sulfides and their applications for accessing stereodefined trisubstituted alkenes. Yang, Z.(本科生); Chen, X.; Kong, W.; Xia, S.; Zheng, R.; Luo, F.; Zhu, G.* Org. Biomol. Chem. 2013, 11, 2175-2185.

2012年

80. Highly stereoselective synthesis of (Z)-1,2-dihaloalkenes by a Pd-catalyzed hydrohalogenation of alkynyl halides. Zhu, G.*; Chen, D.; Wang, Y.; Zheng, R. Chem. Commun. 2012, 48, 5796-5798. 54

81. Preparation of 3,4,5-Trisubstituted Oxazolones by Pd-Catalyzed Coupling of N-Alkynyl tert-Butyloxycarbamates with Aryl Halides and Related Electrophiles. Lu, Z.; Cui, W.; Xia, S.; Bai, Y.; Luo, F.; Zhu, G.* J. Org. Chem. 2012, 77, 9871-9877. 

82. A Facile Access to 3,5-Disubstituted Oxazolones Featuring a Cu-catalyzed Cyclization of N-Alkynyl tert-Butyl Carbamates. Lu, Z.; Yang, Z.; Cui, W.; Zhu, G.* Chem. Lett. 2012, 41, 636-638.

83. Approach to highly functionalized oxazolones by a Pd-catalyzed cyclization of N-alkynyl tert-butyloxycarbamates. Lu, Z.; Xu, X.; Yang, Z.; Kong, L.*; Zhu, G.* Tetrahedron Lett. 2012, 53, 3433-3436. 

84. A Facile Method for the Synthesis of 3-Alkyloxindole. Du, T.; Zhu, G.*; Zhou, J.* Lett. Org. Chem. 2012, 9, 225-232.

2011年

85. Palladium-catalyzed haloallylation of aromatic ynol ethers with allyl chlorides: a highly regio- and stereoselective approach to (1E)-α-chloroenol ethers. Cai, H.(本科生); Yuan, Z.; Zhu, W.; Zhu, G.* Chem. Commun. 2011, 47, 8682-8684. 

86. Palladium-catalyzed highly regio- and stereoselective synthesis of (1E)- or (1Z)-1,2-dihalo-1,4-dienes via haloallylation of alkynyl halides. Chen, X.; Kong, W.; Cai, H.; Kong, L.; Zhu, G.* Chem. Commun. 2011, 47, 2164-2166. 

87. Palladium-Catalyzed Dienylation of Haloalkynes Using 2,3-Butadienyl Acetates: A Facile Access to (1Z)-1,2-Dihalo-3-vinyl-1,3-dienes. Chen, D.; Chen, X.; Lu, Z.; Cai, H.; Shen, J.; Zhu, G.* Adv. Synth. Catal. 2011, 353, 1474-1478. 

88. Synthesis of Multisubstituted Enamides via Pd-Catalyzed Chloroallylation of Ynamides. Lu, Z.; Kong, W.; Yuan, Z.; Zhao, X.; Zhu. G.* J. Org. Chem. 2011, 76, 8524-8529. 

89. Palladium-Catalyzed Coupling of Haloalkynes with Allyl Acetate: A Highly Regio- and Stereoselective Synthesis of (Z)-β-Haloenol Acetates. Chen, X.; Chen, D.; Lu, Z.; Kong, L.; Zhu, G.* J. Org. Chem. 2011, 76, 6338-6343. 

90. Synthesis of cis-1,2-Dihaloalkenes Featuring Palladium-Catalyzed Coupling of Haloalkynes and α,β-Unsaturated Carbonyls. Chen, D.; Cao, Y.; Yuan, Z.; Cai, H.; Zheng, R.; Kong, L.; Zhu, G.* J. Org. Chem. 2011, 76, 4071-4074. 

2010年

91. Highly efficient and diastereoselective synthesis of 1,3-oxazolidines featuring a palladium-catalyzed cyclization reaction of 2-butene-1,4-diol derivatives and imines. Chen, D.; Chen, X.; Du, T.; Kong, L.; Zheng, R.; Zhen, S.; Wen, Y.; Zhu, G.* Tetrahedron Lett. 2010, 51, 5131-5133.

博士及博士后阶段

92. A Tunable Mimics of Pyridoxal-5’-phosphate (PLP) Catalyst for Schiff Base Exchange and Amine Deprotonation. Felten, A.; Zhu, G.; Aron, Z.* Org. Lett. 2010, 12, 1099-1101.

93. Efficient and Selective Synthesis of (S,R,R,S,R,S)-4,6,8,10,16,18-Hexamethyldocosane via Zr-Catalyzed Asymmetric Carboalumination of Alkenes (ZACA Reaction). Zhu, G.; Liang, B.; Negishi, E.* Org. Lett. 2008, 10, 1099-1101.

94. 1,4-Pentenyne as a Five-Carbon Synthon for Efficient and Selective Syntheses of Natural Products Containing 2,4-Dimethyl-1-penten-1,5-ylidene and Related Moieties via Zr-Catalyzed Carboalumination of Alkynes and Alkenes. Zhu, G.; Negishi, E.* Chem. Eur. J. 2008, 14, 311-318.

95. Fully Reagent-Controlled Asymmetric Synthesis of (–)-Spongidepsin via the Zr-Catalyzed Asymmetric Carboalumination of Alkenes (ZACA Reaction). Zhu, G.; Negishi, E.* Org. Lett. 2007, 9, 2771-2774.

96. Zirconium-Catalyzed Asymmetric Carboalumination of Alkenes (ZACA)^_Lipase-Catalyzed Acetylation Synergy. Huang, Z.; Tan, Z.; Novak, T.; Zhu, G.; Negishi, E.* Adv. Synth. Catal. 2007, 349, 539-545.

97. Zirconium-Catalyzed Methylalumination of Heterosubstituted Arylethynes. Factors Affecting the Regio-, Stereo-, and Chemoselectivities. Wang, G.; Zhu, G.; Negishi, E.* J. Organomet. Chem. 2007, 692, 4731-4736.

98. Palladium-Catalyzed Cyclization via Carbopalladation and Acylpalladation. Negishi, E.*; Wang, G.; Zhu, G. Topics in Organometallic Chemistry, 2006, 19, 1-48. 

99. Transition Metal-Catalyzed Intramolecular Enyne Cyclization Reaction. Zhang, Z.*; Zhu, G.; Tong, X.; Wang, F.; Xie, X.; Wang, J.; Jiang, L. Curr. Org. Chem. 2006, 10, 1457-1478.

100. Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,6-Enynes: Reaction Scope and Mechanism. Zhu, G.; Tong, X.; Cheng, J.; Sun, Y.; Li, D.; Zhang, Z.* J. Org. Chem. 2005, 70, 1712-1717.

101. cis-Chloropalladation of 1,6-Enynes. Zhu, G.; Zhang, Z.* J. Org. Chem. 2005, 70, 3339-3341.

102. A Concise Synthesis of 2-Diarylphosphino-20-methoxy-1,10-binaphthalenes (MOPs) by Simple Resolution. Luo, Y.; Wang, F.; Zhu, G.; Zhang, Z.* Tetrahedron Asymmetry 2004, 15, 15-17.

103. Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,2,7-trienes. Zhu, G.; Zhang, Z.* Org. Lett. 2004, 6, 4041-4044.

104. Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,6-Enynes. Zhu, G.; Zhang, Z.* Org. Lett. 2003, 5, 3645-3648.

学术报告：

1. Controllable carbocyclization of internal alkynes initiated by radical fluoroalkylation, The 24th International Symposium on Fluorine Chemistry, Shanghai, Invited lecture, 2024.07.30。 

2. 5-Endo- and 4-exo-selective carbocyclizations initiated by radical addition to alkynes, The 16th International Symposium for Chinese Organic Chemists, Beijing, Oral lecture, 2023.08.29。

3. 5-Endo-trig和4-exo-trig自由基环化的调控：一种氟效应的发现，中国化学会第十七届全国氟化学会议，江苏南京，邀请报告，2023.07.09。

4. 自由基加成启动的非末端炔烃远程碳氢官能团化反应，第三届全国有机自由基会议，湖北武汉，邀请报告，2022.08.04。

5. 自由基介导的炔烃5-Endo碳环化反应研究，第十七届全国有机合成化学学术研讨会，山东济南，邀请报告，2022.11.12。

6. 自由基迁移引发的远程碳氢官能团化反应研究，第十七届江淮有机化学论坛，台州，2019.11.03。

7. 炔烃自由基加成启动的远程碳-氢键官能团化反应，2019世界青年科学家峰会-绿色化学国际论坛，2019.10.26。

8. 自由基迁移引发的远程醛基直接官能团化反应研究, 第二届全国有机自由基化学会议，深圳，2019.04.14。

9. 醛基的氧化自由基加成反应研究，第31届中国化学会学术年会，浙江杭州，2018.05.07。

10. 醛基参与的自由基转化反应研究，有机合成与药物化学研讨会，复旦大学，2018.08.28。

11. 远程醛基碳-氢键的直接官能团化反应研究，第十届全国有机化学学术会议，广东深圳，2017.12.19。

12. 醛直接转化为酮的催化自由基反应研究，第十五届全国均相催化学术讨论会，浙江杭州，2017.09.28。

13. Transition-Metal-Catalyzed Radical Transformation of Aldehydes for the Synthesis of Carbonyl Compounds，第一届全国有机自由基化学会议，苏州，2017.11.04。

授权专利：

1、 顺式-1-卤-2-氯代烯烃及其制备方法和应用，朱钢国、陈东旭，专利号：ZL 201210004757.9，授权时间：2013.11.27。

2、 一种莽草酸的合成方法，朱钢国、崔伟剑、夏思苑、何祖莺，专利号：ZL 201210094437.7，授权时间：2013.11.27。

3、 一种3,4,5-三取代噁唑-2-酮的合成方法，朱钢国、卢增辉、刘鸽、罗芳、夏思苑，专利号：ZL 201210283568.X，授权时间：2014.11.05。

4、 一种利用顺式-1-卤-2-氯代烯烃合成维生素A的方法，朱钢国，陈东旭，专利号：ZL 201310350098.9，授权时间：2014.11.05。

5、 一种替马罗汀的合成方法，朱钢国、李英龙、金雅丽、金发根、吴平、楼益义，专利号：ZL 201310362839.5，授权时间：2015.01.14。

6、 一种奥司他韦的合成方法，朱钢国、杜思全、章洁妮、程存归，专利号：ZL 201410102788.7，授权时间：2015.05.27。

7、 一种多环酮的制备方法，朱钢国、车超、黄倩雯、郑汉良，专利号：ZL 201510874900.3，授权时间：2018.03.20。

8、 一种ε-三氟甲基取代酰胺制备方法，朱钢国，刘水有，罗芳，黄倩雯，专利号： ZL 201610341590.3，授权时间：2018.06.26。

9、 一种2-氨基-5-叠氮基甲基呋喃的制备方法，朱钢国，黄倩雯，罗芳，郑汉良，刘水有，郭冬梅，专利号：ZL 201610513894.3，授权时间：2018.06.29。

10、 一种3,4-环戊基-1-萘满酮的制备方法，朱钢国，朱慧，罗芳，黄倩雯，专利号：ZL 201610157549.0，授权时间：2018.09.11。

11、 一种二苯并环庚烷衍生物的制备方法，朱钢国，卢丹阳，罗芳，专利号：ZL 201610911768.3，授权时间：2019.03.08。

12、 一种2-三氟甲基-1,4-萘醌衍生物的制备方法，朱钢国，张岩，罗芳，金伟伟，专利号：ZL 201611083500.1，授权时间：2019.07.30。

13、 一种6-二氟烷基酮的制备方法，朱钢国，聂新亮，罗芳，程存归，郭冬梅，专利号：ZL201611237852.8，授权时间：2019.08.06。

14、 一种1,1-二氟四氢萘化合物的制备方法，朱钢国，聂新亮，罗芳，程存归，郭冬梅，专利号：ZL201611236824.4，授权时间：2019.09.06。

15、 一种1,4-二酮化合物的制备方法，朱钢国，车超，周雨露，马倩倩，专利号：ZL201810107336.6，授权时间：2020.04.17。

16、 一种多取代吡咯化合物的制备方法，朱钢国，吴明昌，谢佳燕，罗芳，ZL 201910079281.7，授权时间：2020.09.01。

17、 一种2-三氟甲基-1-茚酮及其衍生物和制备方法，朱钢国，刘芷成，罗芳，孔黎春，ZL 201710217745.7，授权时间：2020.09.01。

18、 一种(Z)式氟烷基化烯基硼酸酯及其制备方法和应用，朱钢国，王帅峰，孔黎春，罗芳，ZL 201810833505.5，授权时间：2020.11.06。

19、 一种(Z)-4-二氟烷基-5-硫烷基-4-戊烯酮衍生物及其制备方法，朱钢国，商甜波，周雨露，ZL 201910916314.9，授权时间：2021.03.26。

20、 一种β-二氟烷基炔烃的制备方法，朱钢国，金伟伟，罗芳，孔黎春，ZL 201810466627.4，授权时间：2021.04.16。

21、 一种氯代环成酮衍生物及其合成方法，朱钢国，勒思雅，邱佳燕，罗芳，孔黎春，ZL 2022106776805，授权时间：2023.05.16.